Dapagliflozin + Linagliptin

Introduction

Dapagliflozin + Linagliptin is a combination of two antidiabetic medicines used to manage blood sugar levels in adults with Type 2 Diabetes Mellitus. Dapagliflozin belongs to a class of drugs known as SGLT2 inhibitors, while Linagliptin is a DPP-4 inhibitor. Together, they help improve glycemic control in diabetic patients when lifestyle changes and other medications do not provide sufficient results. This combination helps reduce the risk of complications associated with high blood sugar levels, including nerve damage, kidney issues, and heart disease.

Uses of Dapagliflozin + Linagliptin

• Used to treat Type 2 Diabetes Mellitus
• Helps manage blood sugar levels in adults
• Used when diet, exercise, or single drug therapy is inadequate

How Dapagliflozin + Linagliptin works

Dapagliflozin helps remove excess glucose through the urine by blocking the SGLT2 protein in the kidneys. Linagliptin works by increasing insulin release and decreasing glucose production in the liver by inhibiting the DPP-4 enzyme. Together, they effectively reduce blood sugar levels.

Benefits of Dapagliflozin + Linagliptin

• Provides better blood sugar control
• Reduces the risk of diabetes-related complications
• Promotes weight loss and lowers blood pressure
• Convenient once-daily dosage

How to take Dapagliflozin + Linagliptin

This medicine should be taken once daily with or without food, as prescribed by your doctor. Swallow the tablet whole with water. Take it at the same time each day for best results. Do not skip doses or stop without medical advice.

Type of Dosage Available

• Tablet (Oral use)
• Fixed-dose combination strength may vary (consult your doctor)

Side effects of Dapagliflozin + Linagliptin

• Urinary tract infections
• Low blood sugar (hypoglycemia)
• Frequent urination
• Headache
• Nausea
• Dehydration
• Allergic skin reactions (rare)

Safety Advice

• Not recommended for Type 1 diabetes or diabetic ketoacidosis
• Inform your doctor if you have kidney or liver issues
• Monitor blood sugar regularly while using this medicine
• Not advisable during pregnancy or breastfeeding unless prescribed
• Maintain adequate hydration to avoid dehydration

Frequently Asked Questions (FAQs)

Q: Can I take Dapagliflozin + Linagliptin with insulin?
A: Yes, but only under a doctor's supervision, as combining with insulin increases the risk of low blood sugar.

Q: Is this medicine suitable for kidney patients?
A: Dose adjustments may be needed. Inform your doctor if you have kidney disease.

Q: Can I stop the medicine if my sugar levels normalize?
A: No, continue taking it as prescribed. Stopping it abruptly may spike blood sugar levels again.

Q: Does this combination cause weight loss?
A: Yes, Dapagliflozin may promote mild weight loss due to glucose loss through urine.

Q: What should I do if I miss a dose?
A: Take it as soon as you remember. If it's close to the next dose, skip the missed one. Do not double the dose.