Letrozole

Letrozole is a medication primarily used to treat hormone receptor-positive breast cancer in postmenopausal women. It belongs to the class of aromatase inhibitors, which work by reducing estrogen levels in the body. Lowering estrogen helps slow or stop the growth of certain breast cancer cells. Letrozole is also used for treating infertility in women with ovulation problems. It is often prescribed as part of fertility treatments to stimulate ovulation. This medicine should be taken under medical supervision to ensure safety and effectiveness.

Uses of Letrozole

• Treatment of hormone receptor-positive breast cancer
• Helps prevent the recurrence of breast cancer
• Used in fertility treatment for women with ovulation disorders
• May be prescribed for polycystic ovary syndrome (PCOS)

How Letrozole Works

Letrozole blocks the enzyme aromatase, which converts androgens into estrogen. By reducing estrogen levels, it slows the growth of estrogen-dependent cancer cells. In fertility treatments, it stimulates ovulation by increasing follicle-stimulating hormone (FSH) production.

Benefits of Letrozole

• Effectively treats breast cancer in postmenopausal women
• Reduces the risk of breast cancer recurrence
• Helps women with fertility issues by inducing ovulation
• Can be used as an alternative to Clomiphene in PCOS treatment

How to Take Letrozole

Letrozole should be taken as prescribed by your doctor. It is usually taken once daily with or without food. If using it for fertility treatment, follow your doctor’s instructions regarding dosage and timing.

Type of Dosage Available

• Tablet form (2.5 mg)

Side Effects of Letrozole

• Hot flashes
• Fatigue and dizziness
• Increased sweating
• Joint and muscle pain
• Nausea
• Osteoporosis risk with prolonged use

Safety Advice

• Not recommended for premenopausal women unless prescribed for fertility
• Avoid alcohol to minimize dizziness and fatigue
• Consult a doctor before use if you have liver or kidney disease
• May cause bone thinning; calcium and vitamin D supplements may be advised
• Not safe during pregnancy and breastfeeding

Frequently Asked Questions (FAQs)

Q: How long does Letrozole take to work for infertility?

A: It typically stimulates ovulation within 5 to 7 days of taking the dose.

Q: Can Letrozole be used for breast cancer prevention?

A: Yes, it is sometimes prescribed to reduce the risk of recurrence in high-risk women.

Q: Does Letrozole cause weight gain?

A: Weight gain is not a common side effect, but some women may experience it.

Q: Can Letrozole be taken long-term?

A: For breast cancer, it may be taken for up to 5 years as prescribed by the doctor.

Q: Can Letrozole improve pregnancy chances?

A: Yes, it is commonly used in fertility treatments to induce ovulation.