Macitentan

Introduction

Macitentan is a prescription medicine mainly used to treat Pulmonary Arterial Hypertension (PAH), a condition in which blood pressure becomes high in the arteries of the lungs. This increases the workload on the heart and may cause symptoms like shortness of breath, tiredness, and swelling in the legs. Macitentan helps relax and widen the blood vessels in the lungs, improving blood flow and reducing strain on the heart. It is usually advised for long-term management of PAH and should be taken exactly as prescribed by a doctor.

Uses of Macitentan

• Pulmonary arterial hypertension (PAH)
• Improves exercise ability in PAH patients
• Delays disease progression in PAH

How Macitentan works

Macitentan blocks endothelin receptors, which are responsible for blood vessel narrowing. This action relaxes the pulmonary arteries, reducing blood pressure in the lungs.

Benefits of Macitentan

• Improves breathing and exercise tolerance
• Reduces pressure in lung arteries
• Slows down PAH progression
• Can be used long-term for chronic management

How to take Macitentan

Take Macitentan as prescribed by your doctor, usually once daily with or without food. Do not skip doses and follow your doctor `s instructions carefully for best results.

Type of Dosage Available

• Tablet

Side effects of Macitentan

• Headache
• Anemia
• Nasal congestion
• Flushing
• Swelling of hands or feet
• Liver function abnormalities

Safety advice

• Regularly monitor liver function and hemoglobin levels
• Not recommended during pregnancy; may harm the unborn baby
• Use effective contraception if you are of childbearing potential
• Inform your doctor of any liver or heart conditions
• Do not use without a prescription

Frequently Asked Questions (FAQs)

Q. What is Macitentan used for?
A. Macitentan is used to treat pulmonary arterial hypertension (PAH) by relaxing blood vessels in the lungs.

Q. How long does it take for Macitentan to show results?
A. Improvement in symptoms may be noticed within a few weeks, but it is usually prescribed for long-term use.

Q. Can Macitentan be taken during pregnancy?
A. No, it should not be taken during pregnancy as it may harm the baby.

Q. Are there any regular tests required while taking Macitentan?
A. Yes, regular liver function tests and hemoglobin levels should be monitored.

Q. Is Macitentan safe for long-term use?
A. Yes, when taken under medical supervision, it is considered safe for long-term management of PAH.