Metformin + Gemigliptin

Introduction

Metformin + Gemigliptin is a combination medicine used to manage type 2 diabetes mellitus. Metformin is a biguanide that lowers blood sugar by reducing glucose production in the liver and increasing insulin sensitivity. Gemigliptin is a DPP-4 inhibitor that enhances the body's natural insulin release after meals. Together, this combination helps regulate blood sugar levels effectively, especially when lifestyle changes alone are insufficient. It is commonly prescribed as part of a comprehensive diabetes management plan.

Uses of Metformin + Gemigliptin

• Management of type 2 diabetes mellitus
• Helps in achieving better glycemic control
• Used when diet and exercise alone do not control blood sugar
• May be used alone or with other antidiabetic medications
• Reduces the risk of diabetes-related complications

How Metformin + Gemigliptin works

Metformin decreases glucose production in the liver and increases insulin sensitivity. Gemigliptin inhibits the DPP-4 enzyme, which increases levels of incretin hormones, promoting insulin release and lowering post-meal glucose levels. Together, they offer dual action in controlling blood sugar.

Benefits of Metformin + Gemigliptin

• Improves fasting and post-meal blood sugar levels
• Reduces insulin resistance
• Low risk of hypoglycemia (low blood sugar)
• Supports long-term blood sugar management
• Convenient once or twice daily dosing

How to take Metformin + Gemigliptin

Take the medicine as prescribed by your doctor, usually once or twice daily with meals to reduce gastrointestinal side effects. Swallow the tablet whole with water. Do not skip doses and do not stop the medicine without consulting your doctor. Maintain a balanced diet and regular exercise while on this medication.

Type of Dosage Available

• Tablet

Side effects of Metformin + Gemigliptin

• Nausea or vomiting
• Stomach upset or diarrhea
• Loss of appetite
• Headache
• Metallic taste in the mouth
• Low blood sugar (rare, usually with other medicines)

Safety Advice

• Not recommended for patients with severe kidney or liver disease
• Avoid alcohol as it may increase the risk of lactic acidosis
• Inform your doctor if you are pregnant or breastfeeding
• Monitor blood sugar regularly as advised
• Take with meals to reduce stomach-related side effects

Frequently Asked Questions (FAQs)

Q: What is Metformin + Gemigliptin used for?
A: It is used to control blood sugar levels in people with type 2 diabetes, especially when diet and exercise are not enough.

Q: Can Metformin + Gemigliptin cause hypoglycemia?
A: It rarely causes hypoglycemia on its own but may increase the risk when combined with other antidiabetic medicines or missed meals.

Q: When should I take this medicine?
A: It is best taken with meals to avoid stomach upset. Follow your doctor’s instructions regarding timing and frequency.

Q: Is this combination safe during pregnancy?
A: Inform your doctor if you are pregnant or planning pregnancy. The use of this medicine during pregnancy should be evaluated by a healthcare professional.

Q: Can I stop the medicine if my sugar is under control?
A: No, do not stop the medicine without consulting your doctor, even if your sugar levels improve. It is part of long-term diabetes management.