Pioglitazone + Metformin

Pioglitazone + Metformin is a combination medication used to control high blood sugar in individuals with type 2 diabetes. Metformin reduces glucose production in the liver and improves insulin sensitivity, while pioglitazone enhances the body’s response to insulin. Together, they help manage blood glucose levels effectively, reduce complications related to diabetes, and improve overall metabolic health. This combination is often prescribed when metformin alone is not sufficient to manage blood sugar. Regular use of this medicine, along with diet and exercise, can lead to better glycemic control and prevent long-term complications.

Uses of Pioglitazone + Metformin

• Type 2 Diabetes Mellitus
• Improves insulin sensitivity
• Reduces blood glucose levels
• Used when single therapy is not effective

How Pioglitazone + Metformin Works

Metformin decreases liver glucose production and increases insulin sensitivity. Pioglitazone enhances the body’s ability to use insulin effectively. Together, they lower blood sugar and improve glucose uptake in the body.

Benefits of Pioglitazone + Metformin

• Effective control of blood sugar
• Prevents complications like kidney damage and nerve issues
• Improves insulin sensitivity
• Supports weight management in some patients
• Combines two mechanisms for better glucose control

How to Take Pioglitazone + Metformin

Take the medication as prescribed by your doctor, usually once or twice daily with meals to reduce stomach upset. Swallow the tablet whole with water. Do not skip doses or take more than recommended. Monitor blood sugar levels regularly.

Type of Dosage Available

• Metrose p 15 tablet - Pioglitazone 15mg & Metformin Hydrochloride 500mg
   
• Extended-release tablet

Side Effects of Pioglitazone + Metformin

• Nausea or vomiting
• Stomach discomfort
• Weight gain
• Low blood sugar (when combined with other diabetes medications)
• Swelling or fluid retention
• Lactic acidosis (rare but serious)

Safety Advice

• Inform your doctor about kidney or liver conditions
• Not recommended for type 1 diabetes
• Regularly monitor blood sugar and kidney function
• Avoid alcohol to reduce the risk of lactic acidosis
• Use with caution in elderly patients

Frequently Asked Questions (FAQs)

Q. What is Pioglitazone + Metformin used for?
A. It is used to manage high blood sugar levels in people with type 2 diabetes when metformin alone is not sufficient.

Q. Can I take this medication with food?
A. Yes, it should be taken with meals to minimize stomach upset and improve absorption.

Q. Are there any serious side effects of this combination?
A. Rarely, it may cause lactic acidosis or fluid retention. Seek medical help if you experience breathing difficulty, muscle pain, or unusual fatigue.

Q. Is this medicine safe during pregnancy?
A. It should only be used if prescribed by your doctor. Inform your doctor if you are pregnant or planning to conceive.

Q. What precautions should I take while on this medicine?
A. Monitor your blood sugar regularly, avoid alcohol, and inform your doctor of any kidney, liver, or heart conditions.