Repaglinide + Metformin

Introduction

Repaglinide + Metformin is a combination antidiabetic medication used to manage type 2 diabetes mellitus in adults. Repaglinide stimulates the pancreas to produce more insulin, helping control blood sugar levels after meals. Metformin decreases glucose production in the liver and improves the body's response to insulin. This dual-action therapy helps improve glycemic control in individuals whose blood sugar is not adequately controlled by diet, exercise, or single medication therapy.

Uses of Repaglinide + Metformin

• Management of type 2 diabetes mellitus
• Helps lower blood sugar levels post meals
• Improves insulin sensitivity
• Reduces risk of diabetes-related complications
• Used when single drug therapy is insufficient

How Repaglinide + Metformin works

Repaglinide stimulates insulin secretion from the pancreas, especially after meals, while Metformin decreases glucose production in the liver and increases insulin sensitivity. Together, they work synergistically to control blood glucose levels throughout the day.

Benefits of Repaglinide + Metformin

• Effective blood sugar control
• Targets both fasting and postprandial glucose
• Helps reduce insulin resistance
• Can delay complications like neuropathy and retinopathy
• Convenient dual therapy in one tablet

How to take Repaglinide + Metformin

Take this medicine exactly as prescribed by your doctor, usually with meals to reduce gastrointestinal side effects. Do not skip meals while on this medication. Swallow the tablet whole with water and do not crush or chew. Regularly monitor blood glucose levels and follow your prescribed diet and exercise plan.

Type of Dosage Available

• Tablet (oral)
• Extended-release tablet (in some brands)

Side effects of Repaglinide + Metformin

• Nausea or vomiting
• Diarrhea
• Stomach discomfort
• Hypoglycemia (low blood sugar)
• Headache
• Metallic taste in mouth
• Lactic acidosis (rare but serious)

Safety advice

• Do not use in type 1 diabetes or diabetic ketoacidosis
• Inform your doctor if you have kidney or liver problems
• Avoid alcohol while on this medicine
• Monitor blood sugar regularly
• Use cautiously in elderly patients
• Consult your doctor before using during pregnancy or breastfeeding

Frequently Asked Questions (FAQs)

Q: What is Repaglinide + Metformin used for?
A: It is used to manage blood sugar levels in adults with type 2 diabetes when diet and exercise alone are not enough.

Q: Can this combination cause low blood sugar?
A: Yes, especially if meals are skipped or during intense exercise. It’s important to monitor your glucose levels.

Q: Is it safe to take Repaglinide + Metformin daily?
A: Yes, when taken as prescribed by your doctor. It helps maintain consistent blood sugar levels.

Q: Can I take this medicine on an empty stomach?
A: No, it should be taken with meals to minimize the risk of gastrointestinal side effects and hypoglycemia.

Q: What should I do if I miss a dose?
A: Take the missed dose with the next meal. Do not take a double dose to make up for a missed one.