Rifampicin + Isoniazid + Ethambutol

Rifampicin + Isoniazid + Ethambutol is a combination medicine used to treat tuberculosis (TB). It works by killing or stopping the growth of the bacteria that cause TB. This combination is widely prescribed to ensure effective treatment and prevent the development of drug-resistant TB strains. It is taken as part of a long-term TB treatment plan, usually under medical supervision. Completing the full course is essential to prevent relapse and resistance. This medicine is available in tablet form and should be taken as directed by a healthcare professional.

Uses of Rifampicin + Isoniazid + Ethambutol

• Treatment of tuberculosis (TB)
• Prevention of TB recurrence
• Used in combination with other anti-TB drugs
• Helps in reducing the spread of TB infection

How Rifampicin + Isoniazid + Ethambutol Works

Rifampicin blocks bacterial RNA synthesis, preventing bacterial growth. Isoniazid inhibits cell wall formation, leading to bacterial death. Ethambutol disrupts bacterial metabolism, further weakening TB bacteria. Together, these medicines work synergistically to eliminate the TB infection.

Benefits of Rifampicin + Isoniazid + Ethambutol

• Effective against active tuberculosis infection
• Prevents the spread of TB
• Reduces the risk of drug-resistant TB
• Combination therapy improves treatment success

How to Take Rifampicin + Isoniazid + Ethambutol

This medicine should be taken on an empty stomach, preferably one hour before or two hours after a meal. Swallow the tablet whole with water. Follow your doctor’s prescribed dosage and complete the full treatment course to avoid TB relapse or resistance.

Types of Dosage Available

• Rifampicin + Isoniazid + Ethambutol 150 mg/75 mg/275 mg tablet
• Rifampicin + Isoniazid + Ethambutol 300 mg/150 mg/400 mg tablet

Side Effects of Rifampicin + Isoniazid + Ethambutol

• Nausea and vomiting
• Loss of appetite
• Dark-colored urine
• Jaundice (yellowing of skin and eyes)
• Nerve damage causing tingling or numbness
• Vision problems

Safety Advice

• Avoid alcohol as it may increase liver damage risk
• Monitor liver function regularly during treatment
• Inform your doctor if you have kidney or liver disease
• Not recommended during pregnancy unless prescribed
• Use with caution in diabetic patients

Frequently Asked Questions (FAQs)

Q: What is Rifampicin + Isoniazid + Ethambutol used for?
A: It is used to treat tuberculosis (TB) and prevent TB recurrence.

Q: Can I stop taking the medicine once I feel better?
A: No, you must complete the full course to prevent drug-resistant TB.

Q: Are there any dietary restrictions while taking this medicine?
A: Avoid alcohol and certain foods that may affect liver function.

Q: Can I take Rifampicin + Isoniazid + Ethambutol during pregnancy?
A: Consult your doctor before using it during pregnancy.

Q: How long does the treatment for tuberculosis last?
A: TB treatment usually lasts for 6 months or more, depending on the severity.