Sitagliptin + Glimepiride + Metformin

Sitagliptin + Glimepiride + Metformin is a powerful combination medicine used to control high blood sugar levels in people with type 2 diabetes. Sitagliptin is a DPP-4 inhibitor that increases insulin production, Glimepiride is a sulfonylurea that stimulates the pancreas to release more insulin, and Metformin improves insulin sensitivity and reduces glucose production in the liver. Together, these medicines help manage blood sugar effectively, reducing the risk of complications associated with diabetes.

Uses of Sitagliptin Glimepiride Metformin

• Management of type 2 diabetes mellitus
• Control of high blood sugar levels
• Prevention of diabetes-related complications
• Support for long-term glycemic control

How Sitagliptin Glimepiride Metformin works

Sitagliptin increases insulin secretion and lowers glucagon levels, Glimepiride stimulates insulin release from the pancreas, and Metformin reduces liver glucose production and enhances insulin sensitivity. Together, they lower blood sugar levels effectively.

Benefits of Sitagliptin Glimepiride Metformin

• Effective triple therapy for type 2 diabetes
• Improves insulin function and secretion
• Reduces fasting and post-meal blood sugar levels
• Helps prevent kidney, eye, and nerve complications
• Convenient single-pill combination

How to take Sitagliptin Glimepiride Metformin

Take this medicine with meals to reduce stomach upset. Swallow it whole with water. Follow your doctor’s prescribed dosage and do not skip or double doses. Regular monitoring of blood sugar is advised.

Type of Dosage Available

• Tablet

Side effects of Sitagliptin Glimepiride Metformin

• Low blood sugar (hypoglycemia)
• Nausea and vomiting
• Diarrhea
• Headache
• Weight gain (due to Glimepiride)
• Metallic taste
• Lactic acidosis (rare but serious)

Safety advice

• Monitor blood sugar levels regularly
• Avoid alcohol to reduce risk of lactic acidosis
• Inform your doctor if you have kidney or liver issues
• Not recommended during pregnancy or breastfeeding without doctor’s advice
• Maintain a healthy diet and exercise regularly

Frequently Asked Questions (FAQs)

Q. What is Sitagliptin Glimepiride Metformin used for?
A. It is used to manage blood sugar levels in people with type 2 diabetes when diet and exercise alone are not enough.

Q. Can this medicine cause low blood sugar?
A. Yes, especially due to Glimepiride. Always monitor blood sugar and carry a sugar source in case of hypoglycemia.

Q. Should I take this medicine with food?
A. Yes, taking it with food helps reduce gastrointestinal side effects and the risk of low blood sugar.

Q. Can I take this combination if I have kidney problems?
A. Consult your doctor, as dose adjustments or alternative treatment may be required in kidney impairment.

Q. What should I do if I miss a dose?
A. Take the missed dose as soon as you remember. If it's almost time for the next dose, skip the missed one. Do not double the dose.