Tenofovir Alafenamide

Tenofovir Alafenamide is an antiviral medication used to treat HIV infection and chronic Hepatitis B. It belongs to the class of nucleotide reverse transcriptase inhibitors (NRTIs) and helps control the virus by preventing its replication in the body. Compared to older versions, it is more effective at lower doses, reducing side effects on the kidneys and bones. This medicine is usually taken as part of a combination therapy for HIV and requires regular medical supervision.

Uses of Tenofovir Alafenamide

  • Treatment of HIV infection
  • Management of chronic Hepatitis B virus (HBV)
  • Helps in reducing viral load and boosting immunity
  • Used in combination with other antiretroviral drugs for HIV therapy

How Tenofovir Alafenamide Works

Tenofovir Alafenamide works by blocking the action of the enzyme reverse transcriptase, which the virus needs to multiply. This prevents the virus from spreading in the body, thereby reducing the viral load and improving immune function. Compared to Tenofovir Disoproxil Fumarate, it reaches infected cells more efficiently with lower doses, minimizing kidney and bone-related side effects.

Benefits of Tenofovir Alafenamide

  • Effectively controls HIV and Hepatitis B
  • Lower doses reduce kidney and bone side effects
  • Helps maintain a healthy immune system
  • Prevents the progression of liver disease in HBV patients
  • Improves long-term treatment adherence due to fewer side effects

How to Take Tenofovir Alafenamide

Tenofovir Alafenamide is taken once daily, with or without food, as prescribed by a doctor. It is often used in combination with other antiretroviral medications. Do not miss doses, as this can lead to drug resistance. Regular monitoring of kidney and liver function is recommended during treatment.

Types of Dosage Available

  • Tenofovir Alafenamide 25 mg Tablets
  • Combination tablets with other antiretroviral drugs

Side Effects of Tenofovir Alafenamide

  • Headache and dizziness
  • Nausea and stomach pain
  • Fatigue and weakness
  • Increased liver enzyme levels
  • Rare kidney problems

Safety Advice

  • Take as prescribed by a doctor; do not skip doses
  • Monitor kidney and liver function regularly
  • Not recommended for patients with severe liver or kidney disease
  • Avoid alcohol, as it may worsen liver conditions
  • Use effective contraception, as safety during pregnancy is not well established

Frequently Asked Questions (FAQs)

Q: What is Tenofovir Alafenamide used for?
A. It is used to treat HIV and chronic Hepatitis B by reducing viral load and improving immunity.

Q: How should I take Tenofovir Alafenamide?
A. Take one tablet daily, with or without food, as directed by your doctor.

Q: Can Tenofovir Alafenamide cure HIV?
A. No, it controls the virus but does not cure HIV. Lifelong treatment is required.

Q: Are there any serious side effects?
A. Kidney problems and liver enzyme elevations are possible but less common with this version.

Q: Can pregnant women take Tenofovir Alafenamide?
A. Consult a doctor before use, as its safety in pregnancy is not fully established.

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