Terfenadine

Terfenadine is an antihistamine used to relieve allergy symptoms such as sneezing, runny nose, and itchy or watery eyes. It works by blocking histamine, a substance in the body that causes allergic symptoms. Terfenadine is effective for treating hay fever, allergic rhinitis, and urticaria (hives). While it was once commonly prescribed, its use has decreased due to the development of newer antihistamines with fewer side effects. Terfenadine was removed from the market in many regions due to its association with serious heart-related side effects, particularly when taken in higher doses or in combination with other medications.

Uses of Terfenadine

  • Treats allergic rhinitis (hay fever) symptoms
  • Relieves symptoms of urticaria (hives)
  • Reduces sneezing, runny nose, and itchy/watery eyes caused by allergies

How Terfenadine Works

Terfenadine works by blocking histamine receptors in the body, preventing the action of histamine, which is responsible for allergy symptoms such as sneezing, itching, and swelling. By inhibiting histamine’s effect, Terfenadine helps reduce allergic reactions.

Benefits of Terfenadine

  • Provides relief from common allergy symptoms
  • Reduces the frequency and severity of allergic reactions
  • Helps manage symptoms of hay fever and hives

How to Take Terfenadine

Terfenadine was typically taken in oral tablet form, once or twice a day, as prescribed by your healthcare provider. It is important to follow the prescribed dosage and avoid exceeding the recommended amount. Terfenadine should not be taken with certain medications, especially those that affect heart rhythm.

Type of Dosage Available

  • Oral tablets

Side Effects of Terfenadine

  • Headache
  • Drowsiness (although it was less sedating compared to older antihistamines)
  • Heart-related side effects (especially when taken in excess or with other medications)
  • Rash
  • Dizziness

Safety Advice

  • Do not take Terfenadine with other medications that can affect the heart, such as certain antibiotics or antifungals
  • Terfenadine should be used with caution in patients with heart conditions
  • Avoid alcohol while taking Terfenadine
  • Consult your doctor before using Terfenadine if you are pregnant or breastfeeding
  • In some regions, Terfenadine has been withdrawn from the market due to serious side effects

Frequently Asked Questions (FAQs)


Q. What is Terfenadine used for?
A. Terfenadine is used to treat allergy symptoms like sneezing, runny nose, and itching from hay fever, as well as urticaria (hives).

Q. What are the common side effects of Terfenadine?
A. Common side effects include headache, drowsiness, dizziness, and in rare cases, heart-related issues, especially when taken in high doses or with certain medications.

Q. Can Terfenadine be taken with other medications?
A. Terfenadine should not be taken with certain medications that affect heart rhythm. Always consult your healthcare provider before combining it with other drugs.

Q. Is Terfenadine still available for use?
A. Terfenadine has been withdrawn from the market in many regions due to its potential for serious heart-related side effects. Alternatives are available.

Q. Can I drink alcohol while using Terfenadine?
A. It is advised to avoid alcohol while taking Terfenadine as it may increase the risk of side effects, including drowsiness or dizziness.

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