Zidovudine

Zidovudine, also known as AZT, is an antiretroviral medication used to treat HIV (Human Immunodeficiency Virus) infection. It belongs to a class of drugs called nucleoside reverse transcriptase inhibitors (NRTIs). Zidovudine is often used in combination with other antiretroviral medications to slow the progression of HIV, boost the immune system, and improve the quality of life in people living with HIV/AIDS. It may also be used to prevent mother-to-child transmission of HIV during childbirth.

Uses of Zidovudine

• Treatment of HIV-1 infection
• Prevention of mother-to-child transmission of HIV
• Used in post-exposure prophylaxis (PEP)
• Helps reduce the viral load in HIV patients
• Slows progression of HIV to AIDS

How Zidovudine works

Zidovudine works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of the HIV virus. By blocking this enzyme, Zidovudine prevents the virus from multiplying and spreading in the body.

Benefits of Zidovudine

• Reduces HIV viral load
• Improves immune function
• Slows progression to AIDS
• Reduces the risk of HIV transmission
• Effective when used with other antiretrovirals

How to take Zidovudine

Take Zidovudine as prescribed by your doctor. It is usually taken orally with or without food. The dosage is based on your medical condition, weight, and response to treatment. Stick to the prescribed schedule and do not skip doses to ensure effectiveness.

Type of Dosage Available

• Tablet
• Capsule
• Syrup
• Injection

Side effects of Zidovudine

• Headache
• Nausea and vomiting
• Fatigue and weakness
• Anemia
• Muscle pain
• Liver dysfunction (rare)

Safety advice

• Regular blood tests are necessary to monitor blood count
• Inform your doctor of any liver or kidney problems
• Use caution during pregnancy or breastfeeding
• Do not stop the medication without medical advice
• Avoid alcohol and other liver-toxic substances

Frequently Asked Questions (FAQs)

Q. What is Zidovudine used for?
A. Zidovudine is used to treat HIV infection and prevent its transmission, including from mother to child during childbirth.

Q. Can Zidovudine cure HIV?
A. No, Zidovudine cannot cure HIV, but it helps control the infection and improves the patient’s quality of life.

Q. Is Zidovudine safe during pregnancy?
A. Yes, Zidovudine is often used to prevent HIV transmission from mother to baby during pregnancy and delivery under medical supervision.

Q. Can I stop taking Zidovudine if I feel better?
A. No, always follow your doctor’s advice. Stopping the medicine may lead to the virus becoming resistant and worsening your condition.

Q. What should I avoid while taking Zidovudine?
A. Avoid alcohol, and inform your doctor about all other medications you're taking to avoid harmful interactions.