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COMPOSITION:
Sitagliptin (50mg) + Metformin (1000mg)DESCRIPTION:
Introduction
Glura M 50mg/1000mg Tablet is a combination medication designed to help adults manage type 2 diabetes mellitus. It brings together two effective blood sugar-lowering medicines, Sitagliptin and Metformin, into a single tablet. This medication is typically prescribed when diet and exercise alone, or treatment with a single drug, are not enough to control blood glucose levels. By keeping blood sugar within a healthy range, Glura M helps prevent serious long-term complications of diabetes, such as kidney damage, nerve problems, and vision loss, allowing patients to lead a healthier, more active life.
Uses of Glura M 50mg/1000mg Tablet
- Treatment of Type 2 Diabetes Mellitus in adults.
- Assists in achieving glycemic control when Metformin or Sitagliptin alone is insufficient.
- Helps reduce the risk of diabetes-related complications like heart attack or stroke.
How Glura M 50mg/1000mg Tablet Works
This tablet works through a dual-action mechanism. Sitagliptin is a DPP-4 inhibitor that increases insulin release from the pancreas and decreases hormones that raise blood sugar. Metformin is a biguanide that works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and improving the body's sensitivity to insulin. Together, they ensure better regulation of blood sugar levels throughout the day and after meals.
Benefits of Glura M 50mg/1000mg Tablet
- Provides superior blood sugar control compared to single-drug therapy.
- Metformin component is weight-neutral or may assist in modest weight loss.
- Lowers the "bad" glucose (HbA1c) effectively over time.
- Convenient dosing by combining two medications into one pill.
How to Take Glura M 50mg/1000mg Tablet
Always follow your doctor's specific instructions. Generally, this tablet should be swallowed whole with water; do not crush or chew it. It is best taken with food to reduce the chance of an upset stomach. It is vital to take it at the same time every day to maintain a consistent level of medicine in your body. Do not stop taking the medication abruptly without consulting your healthcare provider.
Side Effects of Glura M 50mg/1000mg Tablet
- Nausea or vomiting.
- Upset stomach or diarrhea.
- Upper respiratory tract infection.
- Hypoglycemia (low blood sugar), especially when used with other diabetes medications.
- Rare but serious: Lactic acidosis (characterized by muscle pain or breathing difficulty).
- Rare but serious: Pancreatitis (severe stomach pain).
Safety Advice
- Alcohol: Avoid excessive alcohol consumption as it increases the risk of lactic acidosis.
- Kidney/Liver: Inform your doctor if you have pre-existing kidney or liver disease, as dosage adjustments may be needed.
- Pregnancy/Breastfeeding: Consult your doctor before use, as insulin is often preferred during these periods.
- Driving: Be cautious; if your blood sugar gets too low, it may affect your ability to drive or use machinery.
Frequently Asked Questions (FAQs)
Q: Can I stop taking Glura M once my blood sugar is normal?
A: No, diabetes is a chronic condition. Stopping the medication may cause your blood sugar levels to rise again, increasing the risk of complications. Always consult your doctor before making changes.
Q: Does Glura M cause weight gain?
A: Generally, no. Metformin is known to be weight-neutral or may even cause slight weight loss, making it a preferred choice for many patients.
Q: What should I do if I miss a dose?
A: Take it as soon as you remember with food. However, if it is almost time for your next dose, skip the missed one. Never double the dose to make up for a forgotten tablet.
Q: Is it safe to take this medicine before a surgery?
A: You must inform your surgeon or dentist that you are taking Glura M. You may need to stop taking it temporarily (usually 48 hours before and after) due to the risk of lactic acidosis during certain procedures.
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