Isoniazid + Vitamin B6 (Pyridoxine)

Isoniazid + Vitamin B6 (Pyridoxine) is a combination medicine used primarily in the treatment and prevention of tuberculosis (TB). Isoniazid is an antibiotic that kills Mycobacterium tuberculosis, while Vitamin B6 helps prevent nerve damage (peripheral neuropathy), a common side effect of isoniazid.

Uses of Isoniazid + Vitamin B6 (Pyridoxine)

Treatment of tuberculosis
Prevention of tuberculosis in high-risk individuals
Prevention of isoniazid-induced neuropathy

How Isoniazid + Vitamin B6 (Pyridoxine) Works

Isoniazid inhibits the synthesis of mycolic acids, essential components of the bacterial cell wall, thereby killing the tuberculosis bacteria. Vitamin B6 (Pyridoxine) prevents or treats peripheral neuropathy, a potential side effect caused by isoniazid, by supporting nerve health.

Benefits of Isoniazid + Vitamin B6 (Pyridoxine)

Effective in treating active and latent TB infections
Reduces the risk of drug-induced nerve damage
Helps complete TB treatment safely
Improves compliance with TB therapy

How to Take Isoniazid + Vitamin B6 (Pyridoxine)

This medicine should be taken as prescribed by the doctor, usually once daily on an empty stomach. Swallow the tablet whole with water. Do not skip doses and complete the full course to prevent TB recurrence or resistance.

Type of Dosage Available

Tablets

Side Effects of Isoniazid + Vitamin B6 (Pyridoxine)

Nausea or vomiting
Liver enzyme elevation
Peripheral neuropathy (rare with Vitamin B6)
Fatigue
Loss of appetite
Allergic reactions (rare)

Safety Advice

Avoid alcohol to reduce the risk of liver damage
Inform your doctor of any liver issues before use
Regular liver function monitoring may be advised
Safe during pregnancy if prescribed
Take the full course even if symptoms improve

Frequently Asked Questions (FAQs)

Q. Why is Vitamin B6 given with Isoniazid?
A. Vitamin B6 is given to prevent nerve damage (peripheral neuropathy), a common side effect of Isoniazid.

Q. Can Isoniazid + Vitamin B6 be taken on an empty stomach?
A. Yes, it is usually recommended to take this medicine on an empty stomach for better absorption.

Q. What should I avoid while taking Isoniazid + Vitamin B6?
A. Avoid alcohol and certain foods like aged cheese and cured meats to prevent adverse reactions.

Q. How long should I take Isoniazid + Vitamin B6?
A. The duration depends on your condition; follow your doctor’s prescription and complete the full course.

Q. Is it safe to use during pregnancy?
A. Yes, if prescribed by a doctor, it can be safely used during pregnancy to prevent or treat TB.