Lenvatinib

Lenvatinib is an oral anticancer medication classified as a tyrosine kinase inhibitor. It is primarily used to treat certain types of cancers such as thyroid cancer, liver cancer (hepatocellular carcinoma), and kidney cancer (renal cell carcinoma). Lenvatinib works by blocking specific proteins (kinases) that promote cancer cell growth and the development of blood vessels supplying the tumor. It helps slow the spread of cancer and is typically used when other treatment options have not been effective or are not suitable.

Uses of Lenvatinib

• Thyroid cancer (differentiated type)
• Advanced liver cancer (hepatocellular carcinoma)
• Kidney cancer (renal cell carcinoma)
• Endometrial cancer (in combination therapy)

How Lenvatinib works

Lenvatinib blocks multiple kinase proteins that are involved in cancer cell growth and angiogenesis (blood vessel formation). This helps reduce tumor size and slows the spread of cancerous cells.

Benefits of Lenvatinib

• Targets multiple cancer-causing pathways
• Slows tumor growth and spread
• Improves progression-free survival in cancer patients
• Effective in cases where other treatments fail
• Convenient oral administration

How to take Lenvatinib

Lenvatinib is taken orally once daily with or without food, preferably at the same time each day. The dosage depends on the type of cancer and the patient’s body weight. It should be swallowed whole with water. Follow your doctor’s instructions precisely and do not stop the medicine without consultation.

Type of Dosage Available

• Capsules
• Tablets

Side effects of Lenvatinib

• High blood pressure
• Fatigue
• Loss of appetite
• Diarrhea
• Weight loss
• Hand-foot syndrome (skin reaction)
• Nausea and vomiting
• Liver or kidney function changes
• Bleeding or clotting issues (rare but serious)

Safety advice

• Regularly monitor blood pressure during treatment
• Inform your doctor of liver or kidney disease
• Not recommended during pregnancy or breastfeeding
• May affect fertility in men and women
• Avoid grapefruit juice as it may interfere with the drug
• Inform your doctor about all ongoing medications

Frequently Asked Questions (FAQs)

Q: What is Lenvatinib used for?
A: Lenvatinib is used to treat certain types of thyroid, liver, kidney, and endometrial cancers.

Q: How long should I take Lenvatinib?
A: The duration of treatment depends on your response and tolerance. Your doctor will determine how long you should continue the medication.

Q: Can Lenvatinib cure cancer?
A: Lenvatinib is not a cure but can slow the progression of cancer and improve survival and quality of life.

Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember, unless it is close to the next dose. Do not double up doses.

Q: Can I drink alcohol while on Lenvatinib?
A: It's best to avoid alcohol as it may increase the risk of liver problems or side effects.