Polymyxin B + Neomycin

Introduction

Polymyxin B + Neomycin is a combination of two antibiotics used to treat various bacterial infections, especially those affecting the eyes, ears, and skin. Polymyxin B is effective against Gram-negative bacteria, while Neomycin works against a broad range of bacteria. Together, they offer enhanced antibacterial activity and are commonly used in topical formulations. This combination helps prevent and manage localized infections, particularly when the cause is unknown or mixed bacterial.

Uses of Polymyxin B + Neomycin

• Eye infections such as conjunctivitis
• Ear infections like otitis externa
• Skin infections caused by susceptible bacteria
• Post-surgical wound care
• Burn-related infections

How Polymyxin B + Neomycin Works

Polymyxin B damages the outer membrane of Gram-negative bacteria, leading to leakage of cell contents and bacterial death. Neomycin binds to bacterial ribosomes, inhibiting protein synthesis, and preventing bacterial growth. This dual action enhances the spectrum and effectiveness of the treatment against a wide range of pathogens.

Benefits of Polymyxin B + Neomycin

• Broad-spectrum antibacterial activity
• Effective for eye, ear, and skin infections
• Faster symptom relief
• Reduces risk of infection spread
• Safe and effective when used as directed

How to Take Polymyxin B + Neomycin

Use the medicine exactly as prescribed. For eye or ear drops, clean the area before application. For skin use, apply a thin layer to the affected area. Do not touch the dropper tip or applicator to any surface. Wash hands before and after use. Follow dosage frequency as directed by your doctor.

Type of Dosage Available

• Eye drops
• Ear drops
• Topical cream/ointment

Side Effects of Polymyxin B + Neomycin

• Temporary burning or stinging sensation
• Redness or irritation at the application site
• Allergic reactions (rash, itching, swelling)
• Hearing loss (with prolonged use in ear)
• Kidney damage (rare and usually with systemic absorption)

Safety Advice

• Use under medical supervision only
• Do not apply to deep or puncture wounds
• Avoid prolonged use to prevent resistance
• Inform doctor if you have kidney issues or hearing loss
• Do not use in eyes or ears unless specifically prescribed

Frequently Asked Questions (FAQs)

Q: What is Polymyxin B + Neomycin used for?
A: It is used to treat bacterial infections of the eyes, ears, and skin.

Q: Can I use it without a doctor’s prescription?
A: No, use it only under medical advice to ensure proper treatment and avoid resistance.

Q: Is it safe for children?
A: Yes, but dosage and form should be determined by a pediatrician.

Q: Can it be used for viral or fungal infections?
A: No, it is only effective against bacterial infections.

Q: What should I do if I miss a dose?
A: Apply it as soon as you remember. If it’s almost time for the next dose, skip the missed one.